Cell Signaling Cd15/Ssea1 (Mma) Mouse mAb

Name: Cell Signaling Cd15/Ssea1 (Mma) Mouse mAb
SKU: CSIG-54192S
Price: 385.82 USD

List Price $385.82 Your Price $385.82

Cell Signaling Cd15/Ssea1 (Mma) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-54192S

MFG.PART: 54192S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Source/Isotype	Mouse IgM
Application/Dilution	{IHC Leica Bond: 1:50 - 1:200, Immunohistochemistry (Paraffin): 1:50 - 1:200}
Storage	Supplied as liquid tissue culture supernatant containing sodium azide as a preservative. Stable for 6 months when stored at 4°C. Do not aliquot the antibody.
Specificity/Sensitivity	CD15/SSEA1 (MMA) Mouse mAb recognizes endogenous levels of CD15/SSEA1 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing BALB/C mice injected with U-937 histiocytic cell line.
Background	SSEA1 antibody detects a lactoseries oligosaccharide antigen that is expressed on the surface of mouse embryonal carcinoma and embryonic stem cells (1). This antigen is also found on early mouse embryos and both mouse and human germ cells, but is absent on human embryonic stem and carcinoma cells. Expression of SSEA1 in these human cell types increases upon differentiation, while on the mouse cell types differentiation leads to decreased expression (2).

Specifications