Cell Signaling Ifi6 Antibody

Name: Cell Signaling Ifi6 Antibody
SKU: CSIG-54355S
Price: 320.17 USD

List Price $320.17 Your Price $320.17

Cell Signaling Ifi6 Antibody - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-54355S

MFG.PART: 54355S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	12
Source/Isotype	Rabbit
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	IFI6 Antibody recognizes endogenous levels of total IFI6 protein. This antibody does not cross-react with other ISG12 family proteins.
Species Reactivity	Human
Source/Purification	Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human IFI6 protein. Antibodies are purified by peptide affinity chromatography.
Background	Interferon alpha-inducible protein 6 (IFI6) belongs to the ISG12 family of proteins and is a small, multipass transmembrane protein localized to mitochondrial membranes (1,2). IFI6 is one of the first interferon-stimulated genes to be identified and research studies have shown that IFI6 regulates apoptotic signaling pathways triggered in response to type-I interferons (3,4). In addition, IFI6 participates in type-I interferon-mediated antiviral signaling by mitigating viral replication (5,6).

Specifications