Cell Signaling Perilipin-1 (D1d8) Xp ® Rabbit mAb (Bsa And Azide Free)

Name: Cell Signaling Perilipin-1 (D1d8) Xp ® Rabbit mAb (Bsa And Azide Free)
SKU: CSIG-57117SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling Perilipin-1 (D1d8) Xp ® Rabbit mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-57117SF

MFG.PART: 57117SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H M
Sensitivity	Endogenous
Molecular Weight (kDa)	62
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #9349.
Specificity/Sensitivity	Perilipin-1 (D1D8) XP® Rabbit mAb (BSA and Azide Free) detects endogenous levels of total perilipin-1 protein.
Species Reactivity	Human, Mouse
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues around Ile419 of human perilipin-1 protein.
Background	Triacylglycerol is stored in lipid droplets as a primary energy reserve. Perilipin is localized at the periphery of lipid droplets and serves as a protective coating against lipases (1-3). Evidence suggests that PKA regulates lipolysis by phosphorylating perilipin (1,2,4,5). Phosphorylation of perilipin results in the conformational change that exposes lipid droplets to endogenous lipases, such as hormone-sensitive lipases (2). Hence, perilipin plays a pivotal role in lipid storage (2,5).

Specifications