Cell Signaling Jak1 (6g4) Rabbit mAb (Bsa And Azide Free)

Name: Cell Signaling Jak1 (6g4) Rabbit mAb (Bsa And Azide Free)
SKU: CSIG-77692SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling Jak1 (6g4) Rabbit mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-77692SF

MFG.PART: 77692SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	130
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #3344
Specificity/Sensitivity	Jak1 (6G4) Rabbit mAb (BSA and Azide Free) detects endogenous levels of total Jak1 protein. It does not cross react with other Jak family members.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ile800 of Jak1.
Background	Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4), and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains.

Specifications