Cell Signaling Tnfrsf13c/Baff-R (E3c1q) Rabbit mAb (BSA And Azide Free)

Name: Cell Signaling Tnfrsf13c/Baff-R (E3c1q) Rabbit mAb (BSA And Azide Free)
SKU: CSIG-79406SF
Price: 873.65 USD

List Price $873.65 Your Price $873.65

Cell Signaling Tnfrsf13c/Baff-R (E3c1q) Rabbit mAb (BSA And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-79406SF

MFG.PART: 79406SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	38, 50
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free. For standard formulation of this product see product #62518.
Specificity/Sensitivity	TNFRSF13C/BAFF-R (E3C1Q) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total TNFRSF13C/BAFF-R protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human TNFRSF13C/BAFF-R protein.
Background	B cell-activating factor (BAFF)-receptor (BAFF-R) is a type III transmembrane protein that is expressed almost exclusively on the surface of normal, mature B cells as well as malignant B cells from various forms of B cell lymphoproliferative disorders (1). Unlike BCMA and TACI, BAFF-R only binds BAFF and this interaction plays a fundamental role in driving B cell survival and proliferation by engaging canonical and non-canonical NF-κB signaling modules (2-4). Because its expression is largely restricted to the B cell lineage, BAFF-R is being investigated as an additional immunotherapeutic target for B cell malignancies (5,6).

Specifications