Cell Signaling Ccpg1 (E3c5g) Rabbit mAb

Name: Cell Signaling Ccpg1 (E3c5g) Rabbit mAb
SKU: CSIG-80158S
Price: 354.51 USD

List Price $354.51 Your Price $354.51

Cell Signaling Ccpg1 (E3c5g) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-80158S

MFG.PART: 80158S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	105-120
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:50}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	CCPG1 (E3C5G) Rabbit mAb recognizes endogenous levels of total CCPG1 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human CCPG1 protein.
Background	CCPG1 (cell cycle progression protein 1) was originally identified as a scaffold protein for Rho- specific guanine nucleotide exchange specificity (1). More recently it has been shown to play an important role in ER homeostasis by functioning as a cargo receptor for ER selective autophagy, termed ER-phagy (2). CCPG1 is localized to the ER and is induced by stress (2, 3). It associates with components of autophagy including LC3 family members and the FIP200, a component of the ULK1 complex, facilitating the trafficking of the ER to the autophagosome (2).

Specifications