Cell Signaling Myelin Basic Protein (E9p7u) Mouse mAb

Name: Cell Signaling Myelin Basic Protein (E9p7u) Mouse mAb
SKU: CSIG-83683S
Price: 339.36 USD

List Price $339.36 Your Price $339.36

Cell Signaling Myelin Basic Protein (E9p7u) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-83683S

MFG.PART: 83683S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	12-18
Source/Isotype	Mouse IgG2b kappa
Application/Dilution	{Western Blotting: 1:1000, Immunofluorescence (Frozen): 1:50}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	Myelin Basic Protein (E9P7U) Mouse mAb recognizes endogenous levels of total MBP protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg188 of human MBP protein.
Background	Myelin basic protein (MBP) is an abundant central nervous system (CNS) myelin membrane protein that plays an important role in nerve myelination. Myelin sheaths are multi-layered membranes derived from oligodendrocytes that increase the conduction velocity of axonal impulses. MBP helps to adhere the cytoplasmic leaflets of adjacent oligodendrocyte membranes to one another. Several splice variants of MBP are expressed in cells and the protein is modified following translation (i.e. phosphorylation, methylation), which suggests additional membrane adhesion functions (1).

Specifications