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GenScript Anti-Eculizumab Antibody (13f5), Mab, Mouse; 40ug
List Price $148.00 Your Price $148.00
GenScript Anti-Eculizumab Antibody (13f5), Mab, Mouse - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-A02116-40
MFG.PART: A02116-40
UNSPSC: 12352203
Manufacturer: GenScript USA Inc
Overview
| Specificity | This product is specific for Eculizumab |
| Host Species | Mouse |
| Immunogen | Eculizumab |
| Conjugate | Unconjugated |
Applications
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||
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Properties
| Form | Lyophilized |
| Storage Buffer | This product is lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
| Storage Instructions | The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| Purification | Protein A affinity column |
| Isotype | Mouse IgG1,κ |
| Clonality | Monoclonal |
| Clone ID | 13F5 |
| Note | GenScript can customize this product per customers request including product size, buffer components, etc. |
Background
| Target Background | Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5, or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.Anti-Eculizumab Antibody (13F5), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Eculizumab. |
| Synonyms | Mouse monoclonal to Eculizumab/Soliris |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-A02116-40 |
|---|---|
| Supplier Part Number | A02116-40 |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | GenScript USA Inc |
| Temperature | The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |