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GenScript Anti-Denosumab Ab (3b1), Mab, Mouse; 40ug
List Price $144.00 Your Price $144.00
GenScript An Inhibitory Anti-Idiotype Antibody To Denosumab/Prolia (Target: Rank Ligand). Can Be Used As Capture Antibody Paired With Detection Antibody A02230 - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-A02229-40
MFG.PART: A02229-40
UNSPSC: 12352203
Manufacturer: GenScript USA Inc
Overview
| Specificity | The product is specific for Denosumab. |
| Host Species | Mouse |
| Immunogen | Denosumab F(ab)2 |
| Conjugate | Unconjugated |
Applications
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||
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Properties
| Form | Lyophilized |
| Storage Buffer | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| Storage Instructions | The lyophilized product remains stable for up to 1 year at -20 °C from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| Purification | Protein A affinity column |
| Isotype | Mouse IgG1, κ |
| Clonality | Monoclonal |
| Clone ID | 3B1B7 |
| Note | GenScript can customize this product per customers request including product size, buffer components, etc. |
Background
| Target Background | Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface. |
| Synonyms | Prolia Xgeva, Prolia, AMG 162, AMG-162 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-A02229-40 |
|---|---|
| Supplier Part Number | A02229-40 |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | GenScript USA Inc |
| Temperature | The lyophilized product remains stable for up to 1 year at -20 °C from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |