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Genscriptmonorab™ Anti-Certolizumab Antibody (12a3), Mab, Rabbit; 40 µg
List Price $205.00 Your Price $205.00
GenScript Genscriptmonorab™ Anti-Certolizumab Antibody (12a3), Mab, Rabbit - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-A02269-40
MFG.PART: A02269-40
UNSPSC: 12352203
Manufacturer: GenScript USA Inc
Overview
| Specificity | This product is specific for Certolizumab pegol. |
| Host Species | Rabbit |
| Immunogen | Certolizumab pegol |
| Conjugate | Unconjugated |
Applications
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||
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Properties
| Form | Lyophilized |
| Storage Buffer | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| Storage Instructions | The lyophilized product remains stable for up to 1 year at -20 °C from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| Purification | Protein A affinity column |
| Isotype | Rabbit IgG, κ |
| Clonality | Monoclonal |
| Clone ID | 12A3 |
| Note | GenScript can customize this product per customers request including product size, buffer components, etc. |
Background
| Target Background | Certolizumab pegol, marketed as Cimzia, is a biopharmaceutical drug used to treat Crohns disease, rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. It is a medication that consists of a humanized Fab fragment, derived from an IgG1 antibody, combined with a polyethylene glycol moiety. This modification replaces the Fc region of the antibody. The purpose of removing the Fc region is to prevent complement fixation and antibody-mediated cytotoxicity, while also significantly extending the half-life of the medication. |
| Synonyms | Certolizumab, Cimzia, Certolizumab pegol, anti-TNF drug, CZP, CDP870 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-A02269-40 |
|---|---|
| Supplier Part Number | A02269-40 |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | GenScript USA Inc |
| Temperature | The lyophilized product remains stable for up to 1 year at -20 °C from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |