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GenScript Gmp Anti-Human Cd3 Ab (Okt3), Mab, Mouse; 100ug
List Price $150.00 Your Price $150.00
GenScript Gmp Grade Anti-Human Cd3 Antibody, The Ruo Version Is A02199. Anti-Cd3 Antibody And Anti-Cd28 Antibody Used Together Can Activate T Cells - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-GMPA02199-100
MFG.PART: GMPA02199-100
UNSPSC: 12352203
Manufacturer: GenScript USA Inc
Overview
| Specificity | This product is specificfor Human CD3 |
| Host Species | Mouse |
| Immunogen | Recombinant Human CD3 |
| Conjugate | Unconjugated |
Applications
| ex vivo cell culture process; Flow cytometry |
Properties
| Form | Liquid |
| Storage Buffer | Supplied in 10 mM SodiumCitrate, 150 mM NaCl, 0.02 mg/ml Polysorbate 80, pH 5.0 |
| Concentration | 5 mg/ml |
| Storage Instructions | The productremains stable at -70 ± 10 °C. Avoid repeated freeze-thaw cycles. Please referto the COA for specific expiry date. |
| Isotype | Mouse IgG2a |
| Clonality | Monoclonal |
| Clone ID | OKT3 |
| Note | GMP Anti-Human CD3Antibody (OKT3), mAb, Mouse can be utilized as ancillary materials for Cell,Gene, and Tissue-Based Products and are manufactured under the standards listedbelow: ICH Q7 Good Manufacturing Practice Guide for ActivePharmaceutical Ingredients NMPA: Technical guidelines for pharmaceutical researchand evaluation of immune cell therapy products Guideline and procedure specified in ChinesePharmacopeia |
Quality Control Specifications
| Appearance | Clear, colorless liquid |
| pH | 5.0 ± 0.5 |
| Concentration | 5.0 ± 0.5 mg/ml tested byA280 nm |
| Purity | ≥ 95% as analyzed bySEC-HPLC |
| Sequence | The coverage of the lightchain and heavy chain sequence was 100% consistent with the theoretical aminoacid sequence by mass spectrometry (MS) |
| Residual HCP | ≤ 100.0 ng/mg by ELISAmethod |
| Residual HCD | ≤ 10.0 pg/mg byquantitative PCR method |
| Residual Protein A | ≤ 10.0 ng/mg by ELISAmethod |
| Endotoxin Level | < 0.1 EU/mg by gelclotting method |
| Sterility | Sterile |
| Reactivity | Qualified |
Background
| Target Background | CD3 is a member of theimmunoglobulin superfamily, expressed on T cells. It is composed of fourdistinct chains (ε, γ, δ, ζ). CD3 antigen can form a complex with the T cellreceptor (TCR) to generate an activation signal in T cells, which plays animportant role in the transduction of TCR signal and the activation of bothcytotoxic T cells (CD8 + naïve T cells) and T helper cells (CD4+ naïve T cells). |
For laboratory researchand ex vivo cell isolation andculture applications. Direct human use, including taking orally and injectionand clinical use are forbidden.
| SKU | GSCRPT-GMPA02199-100 |
|---|---|
| Supplier Part Number | GMPA02199-100 |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | GenScript USA Inc |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |