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GenScript Gmp Anti-Human Cd28 Ab (F105), Mab, Mouse; 100ug
List Price $150.00 Your Price $150.00
GenScript Gmp Grade Anti-Human Cd28 Antibody, The Ruo Version Is A02213. Anti-Cd3 Antibody And Anti-Cd28 Antibody Used Together Can Activate T Cells - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-GMPA02213-100
MFG.PART: GMPA02213-100
UNSPSC: 12352203
Manufacturer: GenScript USA Inc
Overview
| Specificity | This product isspecific for Human CD28 |
| Host Species | Mouse |
| Immunogen | Recombinant HumanCD28 |
| Conjugate | Unconjugated |
Applications
| ex vivo cell culture process; Flow cytometry |
Properties
| Form | Liquid |
| Storage Buffer | Supplied in 10 mMSodium Citrate, 150 mM NaCl, pH 6.5. |
| Concentration | 5 mg/ml |
| Storage Instructions | The product remainsstable at -70 ± 10 °C. Avoid repeated freeze-thaw cycles. Please refer to theCOA for specific expiry date. |
| Isotype | Mouse IgG1κ |
| Clonality | Monoclonal |
| Clone ID | F105 |
| Note | GMP Anti-HumanCD28 Antibody (F105), mAb, Mouse can be utilized as ancillary materials forCell, Gene, and Tissue-Based Products and are manufactured under the standardslisted below: ICH Q7 Good ManufacturingPractice Guide for Active Pharmaceutical Ingredients NMPA: Technical guidelinesfor pharmaceutical research and evaluation of immune cell therapy products Guideline and procedurespecified in Chinese Pharmacopeia |
Quality Control Specifications
| Appearance | Clear, colorless liquid |
| pH | 6.5 ± 0.5 |
| Concentration | 5.0 ± 0.5 mg/ml tested by A280 nm |
| Purity | ≥ 95% as analyzed by SEC-HPLC |
| Sequence | The coverage of the light chain and heavy chain sequence was 100%consistent with the theoretical amino acid sequence by mass spectrometry (MS) |
| Residual HCP | ≤ 100.0 ng/mg by ELISA method |
| Residual HCD | ≤ 10.0 pg/mg by quantitative PCR method |
| Residual Protein A | ≤ 10.0 ng/mg by ELISA method |
| Endotoxin Level | < 0.1 EU/mg by gel clotting method |
| Sterility | Sterile |
| Reactivity | Qualified |
Background
| Target Background | CD28 (Cluster ofDifferentiation 28) is one of the proteins expressed on T cells that provideco-stimulatory signals required for T cell activation and survival. It plays animportant role in cell proliferation and cytokine production and promotion ofT-cell survival. It also enhances the production of IL-4 and IL-10 in T cellsin conjunction with TCR/CD3 ligation and CD40L co-stimulation. |
For laboratoryresearch and ex vivo cell isolationand culture applications. Direct human use, including taking orally andinjection and clinical use are forbidden.
| SKU | GSCRPT-GMPA02213-100 |
|---|---|
| Supplier Part Number | GMPA02213-100 |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | GenScript USA Inc |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |