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Millipore Anti-Phosphoserine Antibody, Clone 4a4, Hrp Conjugate Is An Antibody Against Phosphoserine For Use In Wb. - Mill (Additional S&H or Hazmat Fees May Apply)
The identification of protein phosphorylation as a regulatory mechanism originated from studies by Fischer and Krebs in the mid 1950s that later earned them the 1992 Nobel prize. It is the major mechanism for the regulation of diverse cellular processes including cell division, protein synthesis, transcriptional regulation and neurotrans-mission. The steady state phosphorylation of any given substrate is governed by the opposing activities of kinases and phosphatases. It is now believed that a third of all eukaryotic cellular proteins are phosphorylated and that over 95% of all phosphorylation events occur on serine and threonine residues.
Product Information
Format
HRP
Presentation
100 μL of protein G purified mouse IgG1 in PBS containing 0.05% Kathon® and HRP stabilizing compounds. Sufficient for a minimum of 10 immunoblots, if used at the optimum concentration of 1:4000 in 10 mL blocking buffer. Liquid.
Quality Level
MQ100
Applications
Application
Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate is an antibody against Phosphoserine for use in WB.
Key Applications
Western Blotting
Biological Information
Immunogen
Phosphoserine conjugated to KLH.
Epitope
phosphoserine
Clone
4A4
Host
Mouse
Isotype
IgG1
Species Reactivity
All
Species Reactivity Note
Recognizes proteins containing phosphoserine residues, regardless of origin.
Antibody Type
Monoclonal Antibody
Modifications
Phosphorylation
Purification Method
Protein G Purified
Molecular Weight
Varies
Product Usage Statements
Quality Assurance
Routinely evaluated by western blot on RIPA lysates from insulin-treated human HEK293 cells.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
6 months at 2-8°C from date of shipment. NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
