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Key Specifications Table
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| B, M | WB | Rb | Purified | Polyclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | AB10200-25UG |
| Brand Family | Chemicon® |
| Trade Name |
|
| Description | Rb X Bovine Perilipin A |
| Background Information | Perilipin A is the predominant isoform of perilipins a family of proteins which are the most abundant proteins at the surfaces of lipid droplets in adipocytes and are also found in steroidogenic cells. |
| Product Information | |
|---|---|
| Format | Purified |
| Presentation | Purified immunoglobulin presented as a liquid in 0.02M Phosphate buffer,0.25M NaCl,0.1% Sodium Azide, pH 7.6 |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Detect Perilipin A using this Anti-Perilipin A Antibody validated for use in WB. |
| Key Applications |
|
| Application Notes | Suggested dilutions: Western Blot: 0.1-0.2 μg/mL |
| Biological Information | |
|---|---|
| Immunogen | Bovine Perilipin A |
| Concentration | Please refer to lot specific datasheet. |
| Host | Rabbit |
| Species Reactivity |
|
| Antibody Type | Polyclonal Antibody |
| Entrez Gene Number |
|
| Entrez Gene Summary | The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. |
| Gene Symbol |
|
| UniProt Number |
|
| UniProt Summary | FUNCTION: SwissProt: O60240 # Modulator of adipocyte lipid metabolism, it coats lipid storage droplets to protect them to be broken down by hormone- sensitive lipase (HSL). Its absence may result in leanness. SIZE: 522 amino acids; 55950 Da SUBUNIT: Interacts with ABHD5 (By similarity). SUBCELLULAR LOCATION: Lipid droplet (By similarity). Note=Lipid droplet surface-associated (By similarity). TISSUE SPECIFICITY: Adipocytes. PTM: Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet (By similarity). SIMILARITY: SwissProt: O60240 ## Belongs to the perilipin family. |
| Molecular Weight | 64kDa |
| Product Usage Statements | |
|---|---|
| Quality Assurance | Routinely evaluated by immunoblot. |
| Usage Statement |
|
| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain frozen at -20C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze-thaw cycles. |
| Packaging Information | |
|---|---|
| Material Size | 25 μg |