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| Description | |
|---|---|
| Catalogue Number | AB9210-25UL |
| Brand Family | Chemicon® |
| Trade Name |
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| Description | Rb Anti-Insulin Degrading Enzyme |
| Alternate Names |
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| Product Information | |
|---|---|
| Format | Serum |
| Presentation | Rabbit serum. Liquid. |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Anti-Insulin Degrading Enzyme Antibody is an antibody against Insulin Degrading Enzyme for use in WB. |
| Key Applications |
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| Application Notes | Western blotting: 1:10,000-1:20,000. The antibody recognizes a protein of ~110 kDa on rat liver tissue lysate. Optimal working dilutions must be determined by the end user. |
| Biological Information | |
|---|---|
| Immunogen | Synthetic peptide from rat IDE. |
| Concentration | Please refer to lot specific datasheet. |
| Host | Rabbit |
| Specificity | Insulin Degrading Enzyme (IDE). It is expected that the antibody will also react with human and mouse due to immunogen sequence homology. |
| Species Reactivity |
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| Antibody Type | Polyclonal Antibody |
| Entrez Gene Number |
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| Entrez Gene Summary | This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response. |
| Gene Symbol |
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| UniProt Number |
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| UniProt Summary | FUNCTION: SwissProt: P14735 # May play a role in the cellular processing of insulin. May be involved in intercellular peptide signaling. COFACTOR: Binds 1 zinc ion per subunit (By similarity). SIZE: 1019 amino acids; 118022 Da SUBUNIT: Homodimer (Probable). SUBCELLULAR LOCATION: Cytoplasm. PTM: The N-terminus is blocked. SIMILARITY: SwissProt: P14735 ## Belongs to the peptidase M16 family. |
| Product Usage Statements | |
|---|---|
| Quality Assurance | Tested |
| Usage Statement |
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| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. |
| Packaging Information | |
|---|---|
| Material Size | 25 µL |