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Millipore Anti-Tmem16b Antibody Is An Antibody Against Tmem16b For Use In Western Blotting, Ihc & Immunofluorescence. - Mill (Additional S&H or Hazmat Fees May Apply)
Anoctamin-2, also known as Transmembrane protein 16B (TMEM16B) are subunits of Calcium-activated chloride channels (CaCC) which mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC’s but has different biophysical characteristics such as voltage dependence and unitary conductance.
Product Information
Format
Affinity Purified
Presentation
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-TMEM16B Antibody is an antibody against TMEM16B for use in western blotting, IHC & immunofluorescence.
Key Applications
Western Blotting
Immunohistochemistry
Immunofluorescence
Application Notes
Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected TMEM16B in human brain tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TMEM16B in human brain cells.
Biological Information
Immunogen
KLH-conjugated synthetic peptide corresponding to the N-terminus of human TMEM16B.
Epitope
N-terminus
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody will not cross-react with TMEM16A.
Species Reactivity
Human
Rat
Antibody Type
Polyclonal Antibody
Gene Symbol
ANO2
TMEM16B
Purification Method
Antigen Affinity Purified
UniProt Number
Q9NQ90
Molecular Weight
~128 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in rat brain tissue.
Western Blotting Analysis: 2 μg/mL of this antibody detected TMEM16B in rat brain tissue.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
