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Tumor necrosis factor receptor superfamily member 13B
Transmembrane activator and CAML interactor
CD267
Background Information
Members in the TNF superfamily regulate immune responses and induce apoptosis. TACI (also known as Tumor necrosis factor receptor superfamily member 13B, transmembrane activator and CAML interactor, and CD267) binds BAFF and April and its ligands regulate humoral immune responses, activate NF-kB and c-Jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
Product Information
Format
Affinity Purified
Presentation
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality Level
MQ100
Applications
Application
Detect TACI using this Anti-TACI Antibody validated for use in western blotting & ICC.
Key Applications
Western Blotting
Immunocytochemistry
Application Notes
Immunocytochemistry Analysis: 2 μg/mL from a representative lot detected TACI in K562 cells.
Biological Information
Immunogen
KLH-conjugated synthetic peptide corresponding to the N-terminus of human TACI.
Epitope
N-terminus
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Gene Symbol
TNFRSF13B
TACI
Purification Method
Antigen Affinity Purified
UniProt Number
O14836
Molecular Weight
~32 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in K562 and U937 cell lysates.
Western Blotting Analysis: 5 μg/mL of this antibody detected TACI in K562 and U937 cell lysates.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
