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Millipore This Anti-Fezf2 Antibody Is Validated For Use In Western Blotting And Immunohistochemistry (Paraffin) For The Detection Of Fezf2. - Mill (Additional S&H or Hazmat Fees May Apply)
Fezf2 is a transcriptional repressor protein. It is required for the specification of corticospinal motor neurons and other subcerebral projection neurons. FeZf2 also plays a role in the layer and subcortical specific patterning of the subcortical projections and axonal fasciculations that develop in the brain. Fezf2 also controls the development of the dendritic arborization and spines of the large layer V pyramidal neurons. Thus biological processes involving Fezf2 include neuronal patterning, differentiation, neurogenesis, axon guidance, fasciculation, cortex development, anterior/posterior patterning, dendrite development, and locomotory behavior, and it was recently identified as a multipotent progenitor marker for neocortical projection neurons, astrocytes, and oligodendrocytes.
Product Information
Format
Affinity Purified
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
This Anti-Fezf2 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Fezf2.
Key Applications
Western Blotting
Immunohistochemistry (Paraffin)
Application Notes
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Fezf2 in rat spinal cord tissue.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the Engrailed homology 1 repressor domain of human Fezf2.
Epitope
Engrailed homology 1 repressor domain
Concentration
Please refer to lot specific datasheet.
Host
Rabbit
Species Reactivity
Human
Mouse
Rat
Species Reactivity Note
Human, Mouse, Rat. Predicted to react with Bovine based on 100% sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_060478
Gene Symbol
FEZF2
FEZL
ZNF312
Purification Method
Affinity Purfied
UniProt Number
Q8TBJ5
Molecular Weight
~50 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in mouse E13-14 brain tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Fezf2 in 10 µg of mouse E13-14 brain tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
