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Millipore Anti-Fabp1 Antibody Detects Level Of Fabp1 & Has Been Published & Validated For Use In Fabp1. - Mill (Additional S&H or Hazmat Fees May Apply)
FABP1, also known as Fatty acid-binding protein, Liver Fatty acid-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, or p14, and encoded by the gene FABP1/FABPL, is an important fatty acid binding and transport protein. FABP1 is produced in the liver and is part of a family of lipid carrier proteins. FABP1 facilitate the transfer of fatty acids between extra and intracellular membranes. FABP1 level in the blood is used as a biomarker for obesity and type II diabetes. Additionally, recent research indicates that FABP1 can modulate stellate cell activation and this may lead to diet-induced nonalcoholic fatty liver disease, thus FABP1 is a key focus of metabolic research.
Product Information
Format
Serum
Presentation
Rabbit polyclonal serum with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-FABP1 Antibody detects level of FABP1 & has been published & validated for use in FABP1.
Key Applications
Western Blotting
Application Notes
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected FABP1 in wild type mouse liver cytosol and not in LFABP-1 -/- mouse liver cytosol.
Biological Information
Immunogen
Recombinant protein corresponding to rat FABP1.
Host
Rabbit
Species Reactivity
Human
Mouse
Species Reactivity Note
Human, Mouse. Predicted to react with Rat based on 100% sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_036688
Gene Symbol
Fabp1
Purification Method
Unpurified
UniProt Number
P02692
Molecular Weight
~ 14 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in human liver tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FABP1 in 10 µg of human liver tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
