The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
NETA ALERT: Due to inclement weather our offices are closed today, Monday Feb. 23. We will not be shipping orders.
Millipore Anti-Dpagt1 Antibody Detects Level Of Dpagt1 & Has Been Published & Validated For Use In Dpagt1. - Mill (Additional S&H or Hazmat Fees May Apply)
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, also known as GlcNAc-1-P transferase (G1PT or GPT) or N-acetylglucosamine-1-phosphate transferase, and encoded by the gene name DPAGT1 or DPAGT2, is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. Mutations in this integral endoplasmic reticulum (ER) membrane protein enzyme belongs to the glycosyltransferase family 4 results in the congenital disorder of glycosylation type Ij with symptoms such as severe hypotonia, medically intractable seizures, mental retardation, microcephaly, and exotropia. Recent experiments have shown that DPAGT1 is a target of the Wnt/beta-catenin signaling pathway, with Wnt3a inducing higher DPAGT1 mRNA expression.
Product Information
Format
Affinity Purified
Presentation
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-DPAGT1 Antibody detects level of DPAGT1 & has been published & validated for use in DPAGT1.
Key Applications
Western Blotting
Biological Information
Immunogen
KLH-conjugated synthetic peptide corresponding to the N-terminus of human DPAGT1.
Epitope
N-terminus
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Species Reactivity
Mouse
Antibody Type
Polyclonal Antibody
Gene Symbol
DPAGT1
DPAGT2
Purification Method
Antigen Affinity Purified
UniProt Number
Q9H3H5
Molecular Weight
~42 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in mouse kidney tissue lysate with and without blocking peptide.
Western Blotting Analysis: 1 μg/mL of this antibody detected DPAGT1 in mouse kidney tissue lysate with and without blocking peptide.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
