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Millipore Anti-Tropomyosin 4 Antibody Is An Antibody Against Tropomyosin 4 For Use In Western Blotting & Ihc (Paraffin). - Mill (Additional S&H or Hazmat Fees May Apply)
Tropomyosin-4 is also called Tropomyosin alpha-4 chain and TM30p1. Tropomyosin-4 binds calcium and to actin filaments in muscle and non-muscle cells. Tropomyosin-4 associates with the troponin complex, and plays a role in the regulation of smooth and striated muscle contraction, as well as the stabilization of cytoskeleton actin filaments in non-muscle cells. Tropomyosin-4 is found in cardiac tissue and platelets.
Product Information
Format
Affinity Purified
Control
NIH/3T3 cell lysate
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-Tropomyosin 4 Antibody is an antibody against Tropomyosin 4 for use in western blotting & IHC (Paraffin).
Key Applications
Western Blotting
Immunohistochemistry (Paraffin)
Application Notes
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected Tropomyosin 4 in human prostate cancer sections and human heart sections tissue.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminus of human Tropomyosin 4.
Epitope
C-terminus
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody recognizes the C-terminus of Tropomyosin 4.
Species Reactivity
Human
Mouse
Rat
Species Reactivity Note
Demonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine based on 100% sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_003281
Gene Symbol
TPM4
Purification Method
Affinity Purfied
UniProt Number
P67936
Molecular Weight
~33 kDa observed. The calculated molecular weight is 29 kDa, however Tropomyosin 4 has been shown as a ~33 kDa band in western blots (Brooke, K., et al. (2006). Bone. 39:697-705).
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in NIH/3T3 cell lysate.
Western Blotting Analysis: A 1:2,500 dilution of this antibody detected Tropomyosin 4 in 10 µg of NIH/3T3 cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
