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| Description | |
|---|---|
| Catalogue Number | MAB1406-25UG |
| Brand Family | Chemicon® |
| Trade Name |
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| Description | Anti-Thy 1.1 clone OX-7 |
| Alternate Names |
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| Product Information | |
|---|---|
| Format | Purified |
| Control |
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| Presentation | Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative. |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Anti-Thy-1.1 Antibody, clone OX-7 detects level of Thy-1.1 & has been published & validated for use in FC, IC, IH. |
| Key Applications |
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| Application Notes | Flow Cytometry: 1:10-1:100. Use 10 μl per 10E6 thymocytes. Immunohistochemistry on frozen sections. Immunocytochemistry Optimal working dilutions must be determined by end user. |
| Biological Information | |
|---|---|
| Immunogen | Rat Thy-1 |
| Clone | OX-7 |
| Concentration | Please refer to lot specific datasheet. |
| Host | Mouse |
| Specificity | Directed against the Thy 1.1 antigenic determinant which is a monomorphic determinant within rat strains but polymorphic in the mouse (positive to AKR strain, negative to CVA and BALB/c). Thy-1 antigen is present on a variety of cell types including thymocytes, neuronal cells, T-lymphocytes (mouse), stem cells and immature B cells (rat) and connective tissue (Campbell, 1981). Thy-1 is a glycoprotein, 112 amino acids, which is homologous to immunoglobulin domains (Williams & Gagnon, 1982). MAB1406 can be coupled to sepharose 4-B and used to purify mouse Thy-1.1 and rat Thy-1 antigens (Campbell, 1981; Williams & Gagnon, 1982). MAB1406 can also be used to study the killing of Thy-1 tumor cells with antibody-toxin conjugates (Neville, 1982). |
| Isotype | IgG1 |
| Species Reactivity |
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| Antibody Type | Monoclonal Antibody |
| Entrez Gene Number |
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| Gene Symbol |
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| Purification Method | Protein A Purfied |
| UniProt Number |
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| UniProt Summary | FUNCTION: SwissProt: P04216 # May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. SIZE: 161 amino acids; 17935 Da SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor (By similarity). SIMILARITY: SwissProt: P04216 ## Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| Product Usage Statements | |
|---|---|
| Quality Assurance | Tested |
| Usage Statement |
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| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Packaging Information | |
|---|---|
| Material Size | 25 μg |