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Millipore Anti-Epithelium Endothelial Cells, Clone Phm-5, Cat. No. Mab430-I, Is A Mouse Monoclonal Antibody That Detects Human Human Epithelium/Endothelial Cells And Has Been Tested - Mill (Additional S&H or Hazmat Fees May Apply)
The glomeruli network of capillaries filters the blood and the filtrate then enters the renal tubule. Unlike most capillary beds, the glomerular capillaries exit into efferent arterioles rather than venules. The resistance that exists in efferent arterioles causes sufficient hydrostatic pressure within the glomerulus to provide the force for ultrafiltration. Glomerular endothelial cells that create an interface between blood and tissue compartments are responsible for regulating vasomotor tone, trafficking of leukocytes, and maintenance of maintain hemostasis. Unlike endothelium in other tissues, the normal glomerular endothelium is extremely attenuated, being only about 50 to 150 nm in height around the perimeter of the capillary loops. Glomeruli of human kidneys are shown to be rich sialoglycoprotein, which is chemically distinct from rat podocalyxin. (Ref.: Ballermann, BJ (2005). Kidney Int. 67(5); 1668-1671; Kerjaschki, D., et al. (1986). J. Clin. Invest. 78(5); 1142-1149).
Product Information
Format
Purified
Presentation
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Applications
Application
Anti-Epithelium Endothelial Cells, clone PHM-5, Cat. No. MAB430-I, is a mouse monoclonal antibody that detects human human epithelium/endothelial cells and has been tested for use in Immunohistochemistry (Paraffin).
Key Applications
Immunohistochemistry (Paraffin)
Application Notes
Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution from a representative lot detected Epithelium Endothelial Cells in human cerebral cortex tissue sections.
Biological Information
Immunogen
Human Glomerular cells.
Clone
18.29 (PHM-5)
Concentration
Please refer to lot specific datasheet.
Host
Mouse
Specificity
Clone PHM-5 is a mouse monoclonal antibody that detects human epithelium/endothelial cells.
Isotype
IgG1κ
Species Reactivity
Human
Species Reactivity Note
Human.
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_001018121
Purification Method
Protein G purified
Product Usage Statements
Quality Assurance
Evaluated by Immunohistochemistry (Paraffin) in human kidney tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution of this antibody detected Epithelium Endothelial Cells in human kidney tissue sections.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
