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Millipore Detect Hyaluronan Synthase 2 Using This Mouse Monoclonal Antibody, Anti-Hyaluronan Synthase 2 Antibody, Clone 2b11.1 Validated For Use In Western Blotting & Ihc (Paraffin). - Mill (Additional S&H or Hazmat Fees May Apply)
Hyaluronan synthase 2 (HAS2) is also known as Hyaluronate synthase 2, or Hyaluronic acid (HA) synthase 2. As the name suggests, HAS2 is involved in hyaluronan/hyaluronic acid synthesis. Hyaluronan synthase 2 is expressed in fibroblasts. Chromosomal aberrations involving Hyaluronan synthase 2 may be a cause of lipoblastomas, usually diagnosed in children.
Product Information
Format
Purified
Control
MRC-5 cell lysate
Presentation
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Detect Hyaluronan synthase 2 using this mouse monoclonal antibody, Anti-Hyaluronan synthase 2 Antibody, clone 2B11.1 validated for use in western blotting & IHC (Paraffin).
Key Applications
Western Blotting
Immunohistochemistry (Paraffin)
Application Notes
Western Blotting Analysis: 2.0 µg/mL from a representative lot detected Hyaluronan synthase 2 in 10 µg of K562 cell lysate. Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Hyaluronan synthase 2 in human breast adenocarcinoma cell tissue.
Biological Information
Immunogen
GST-tagged recombinant protein corresponding to the cytoplasmic domain of human Hyaluronan synthase 2.
Epitope
Cytoplasmic domain
Clone
2B11.1
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Specificity
This antibody recognizes the cytoplasmic domain of Hyaluronan synthase 2.
Isotype
IgG2aκ
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_005319
Gene Symbol
HAS2
Purification Method
Protein G Purified
UniProt Number
Q92819
Molecular Weight
~ 64 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in MRC-5 cell lysate.
Western Blotting Analysis: 0.2 µg/mL of this antibody detected Hyaluronan synthase 2 in 200 µg of MRC-5 cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
