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Millipore Anti-Taf15 Antibody, Clone 4d71 Is An Antibody Against Taf15 For Use In Western Blotting & Icc. - Mill (Additional S&H or Hazmat Fees May Apply)
TAF15, also known as TATA-binding protein-associated factor 2N, or 68 kDa TATA-binding protein-associated factor, or TAF(II)68, TAFII68, or RNA-binding protein 56, and encoded by the gene TAF15/RBP56/TAF2N, is a RNA and ssDNA binding protein important in transcription initiation. TAF15 aligns with the RNA polymerase II (Pol II) multiprotein complex that together with other proteins like TBP initiates transcription. TAF15 is ubiquitously expressed, and TAF15 shuttles from the nucleus to the cytoplasm upon activation; methylation of TAF15 appears to guide nuclear localization and transcriptional activity. Translocations involving the TAF15 gene may play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene are associated with amyotrophic lateral sclerosis (ALS) diseases.
Product Information
Format
Purified
Presentation
Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-TAF15 Antibody, clone 4D71 is an antibody against TAF15 for use in western blotting & ICC.
Key Applications
Western Blotting
Immunocytochemistry
Application Notes
Immunocytochemistry Analysis: A 1:500 to a 1:1,000 dilution from a representative lot from an independent laboratory detected TAF15 in HeLa cells.
Biological Information
Immunogen
Recombinant protein corresponding to human TAF15.
Clone
4D71
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Isotype
IgG1κ
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_003478
Gene Symbol
TAF15
RBP56
TAF2N
Purification Method
Protein G Purified
UniProt Number
Q92804
Molecular Weight
~68 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: 0.5 μg/mL of this antibody detected TAF15 in 10 μg of HeLa cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
