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HLA class I histocompatibility antigen,Cw-1 alpha chain
MHC class I antigen Cw*1
Background Information
HLA-C, also known as HLA class I histocompatibility antigen, Cw-1 alpha chain, also known as MHC class I antigen Cw*1, and encoded by the gene HLA-C/HLAC. It contains an alpha and beta (beta-2-microglobulin) chain and interacts with the human herpesvirus 8 MIR1 protein.
Product Information
Format
Purified
Presentation
Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-HLA-C Antibody, clone DT9 is an antibody against HLA-C for use in flow cytometry & IP.
Key Applications
Flow Cytometry
Immunoprecipitation
Application Notes
Flow Cytometry Analysis: A representative lot from an independent laboratory detected HLA-C in peripheral blood CD3+ cells from 200 healthy human donors (Apps, R., et al. (2013). Science. 340(6128):84-91.).
Flow Cytometry Analysis: A representative lot from an independent laboratory detected HLA-C in human PBMCs (Corrah, T. W., et al. (2011). J Virol. 85(7):3367-3374.).
Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated HLA-C from various human cell lines (Braud, V. M., et al. (1998). Curr Biol. 8(1):1-10.).
Biological Information
Immunogen
Purified tamarin MHC class I molecules corresponding to human HLA-C.
Clone
DT9
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Isotype
IgG2bκ
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Gene Symbol
HLA-C
HLAC
Purification Method
Protein G Purified
UniProt Number
P30499
Molecular Weight
41 kDa calculated
Product Usage Statements
Quality Assurance
Evaluated by Flow Cytometry in human PBMCs.
Flow Cytometry Analysis: 1 µg of this antibody detected HLA-C in 1X10E6 human PBMCs.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
