Miltenyi Biotec Identification and Enumeration of Cd99+ Cells By Flow Cytometry; 30 Tests in 60 µL

Miltenyi Biotec Clone REA1174 recognizes the human CD99 antigen, a 32 kDa type I single-chain transmembrane sialoglycoprotein which is also known as E2 antigen or MIC2. The expression level of CD99 is particularly high in thymocytes, T cells, T cell leukemias and lymphomas, subsets of mature plasma cells in the medullary cord of reactive lymph nodes, pancreatic islet cells, granulosa cells of the ovary, Sertoli cells of the testes, but absent on granulocytes. It is involved in T cell–adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane and it acts at the same site as, but independently of, PECAM1. | Clone REA1174 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)