Miltenyi Biotec Identification and Enumeration of Cd159a (Nkg2a)+ Cells By Flow Cytometry; 100 Tests in 200 µL

Miltenyi Biotec Clone REA110 recognizes CD159a, an inhibitory natural killer (NK) cell receptor. CD159a forms heterodimer with CD94 and contains a C-type lectin ectodomain. Inhibitory signal is transmitted by the heterodimer via immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and upon ligand engagement, ITIMs are phosphorylated and transmit signal through docking of various tyrosine phosphatases. CD159a/CD94 binds non-classical MHC class I protein, HLA-E. Expression of CD159a is found mainly on NK cells and on subsets of CD8+ cells. | Additional information: Clone REA110 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)