Miltenyi Biotec Detection of Mouse L-Selectin–Expressing Cells; 30 µg in 200 µL

Miltenyi Biotec Clone MEL14-H2.100 recognizes mouse CD62L, a member of the selectin family of cell adhesion molecules also know as L-selectin. CD62L is important for the homing of lymphocytes to peripheral lymph nodes through high endothelial venules. It also contributes to leukocyte emigration into acute inflammatory sites. CD62L is a glycoprotein expressed on the cell surface of most thymocytes, T cells, B cells, monocytes, dendritic cells, neutrophils, and eosinophils. It is highly expressed on naive T cells and down-regulated upon differentiation due to activation-dependent shedding. CD62L is also expressed on a subset of CCR7highCD44high central memory T cells and on CD4+CD25+ regulatory T cells. - MLTY (Additional S&H or Hazmat Fees May Apply)