Miltenyi Biotec Detection Of Human Or Non-Human Primate Il-7rα+ Cells And Regulatory T Cells; 100 Tests in 200 mL

Miltenyi Biotec Clone MB15-18C9 recognizes the CD127 antigen, which is the α-chain of the interleukin 7 (IL-7) receptor, a type I membrane glycoprotein. Signaling of IL-7 through the IL-7R requires both IL-7Rα and the common cytokine gamma chain (γc). CD127 can be identified on immature B cells through the early pre–B stage, on thymocytes, and on most mature T cells with transient down-regulation upon activation. On regulatory T cells CD127 is absent and its expression is inversely correlated with FoxP3 expression and suppressive function. CD127 is also used by thymic stromal derived lymphopoietin (TSLP) as part of a complex. - MLTY (Additional S&H or Hazmat Fees May Apply)