Miltenyi Biotec Identification And Enumeration Of Hla-A9+ Cells By Flow Cytometry; 30 Tests in 60 mL

Miltenyi Biotec Clone REA127 recognizes HLA A9, a class I human leukocyte antigen (HLA). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of 3 domains, of which one comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells. | Additional information: Clone REA127 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)