Miltenyi Biotec Identification and Enumeration of Cd314 (Nkg2d)+ Cells By Flow Cytometry; 100 Tests in 200 µL

Miltenyi Biotec Clone REA797 recognizes CD314 (NKG2D), a cell surface receptor of the type II transmembrane receptor NKG2 family. It is expressed on NK cells, CD8+ α/β T cells, and γ/δ T cells. Though NKG2D itself possesses no intrinsic signaling capability, ligand engagement while associated to the adaptor proteins DAP10 or DAP12 induces cytolytic activation in NK cells as well as costimulation in certain T cell populations. Ligands for NKG2D are stress-inducible MHC class I–related MICA, MICB, and UL16–binding proteins, expressed predominantly on epithelial cells and numerous carcinomas. | Additional information: Clone REA797 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)