Miltenyi Biotec Identification And Enumeration Of LT-ßr+ Cells By Flow Cytometry; 30 Μg In 200 mL

Miltenyi Biotec Clone REA416 recognizes the mouse lymphotoxin β receptor (LT-βR) antigen, a 61 kD single-pass type I membrane protein which is also known as tumor necrosis factor receptor superfamily member 3 (Tnfrsf3). LT-βR is a member of the TNF receptor family that play a role in the development and organization of lymphoid tissues. Membrane-bound lymphotoxin LTα1LTβ2 and LIGHT (TNFSF14) are members of the TNF family of cytokines. Both are primarily expressed on lymphocytes and each can deliver signals through LT-βR. In contrast, LT-βR is primarily expressed on epithelial, stromal and myeloid cells, but not lymphocytes, suggesting that it may participate in the communication between lymphocytes and surrounding epithelial and stromal cells. | Additional information: Clone REA416 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)