Miltenyi Biotec Identification and Enumeration of Gsk3b Ps9+ Cells By Flow Cytometry; 30 Tests in 60 µL

Miltenyi Biotec Clone REA436 recognizes the human, mouse, and rat glycogen synthase kinase-3 β (GSK3B) phosphorylated at serine 9 (pS9). The GSK-3 family of protein-serine kinases was initially characterized as a regulator of glycogen metabolism. The protein kinase phosphorylates residues on glycogen synthase, the rate-limiting enzyme of glycogen synthesis, that are specifically dephosphorylated in response to insulin. In mammals, two genes encode closely related proteins termed GSK3A and GSK3B. The kinase is highly conserved and has roles in a number of signal transduction pathways regulating cell growth, differentiation, and development. GSK3B activity is regulated negatively by the phosphorylation of serine 9. | Additional information: Clone REA436 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)