Miltenyi Biotec Identification and Enumeration of Il-22+ Cells By Flow Cytometry; 30 Tests in 60 µL

Miltenyi Biotec Clone REA466 recognizes the human interleukin-22 (IL-22) antigen, a secreted molecule which belongs to the IL-10 family of cytokines. IL-22 is produced by immune cells, including T helper cell subsets and innate lymphocytes, but acts only on non-hematopoietic stromal cells, in particular epithelial cells, keratinocytes, and hepatocytes. It plays an important role in host defense at mucosal surfaces as well as in tissue repair. Although IL-22 is beneficial to the host in many infectious and inflammatory disorders, depending on the target tissue it can be pathogenic due to its inherent pro-inflammatory properties, which are further enhanced when IL-22 is released together with other pro-inflammatory cytokines, in particular IL-17. | Additional information: Clone REA466 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)