Miltenyi Biotec Detection of Human Cx3cr1+ Cells; 100 Tests in 200 µL

Miltenyi Biotec CX3CR1 is a transmembrane chemokine receptor with a molecular mass of 40 kDa. It binds the chemokine CX3CL1, also known as fractalkine or neurotactin. Binding of CX3CR1 to the membrane‑bound form of fractalkine promotes cell-cell adhesion, wheras the soluble form induces cell migration of CX3CR1-bearing cells such as monocytes, NK cells, T cells, dendritic cells (DCs), and macrophages including microglia.¹ CX3CR1 plays also an important role in the formation of transepithelial dendrites by intestinal DCs.² Failure in the fractalkine/CX3CR1 interaction may contribute to the development of several inflammatory diseases including atherosclerosis, psoriasis, rheumatoid arthritis, and experimental autoimmune myositis. - MLTY (Additional S&H or Hazmat Fees May Apply)