Cell Signaling Protor-2 (D19a5) Rabbit mAb

Name: Cell Signaling Protor-2 (D19a5) Rabbit mAb
SKU: CSIG-12288S
Price: 354.51 USD

List Price $354.51 Your Price $354.51

Cell Signaling Protor-2 (D19a5) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-12288S

MFG.PART: 12288S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H Mk
Sensitivity	Endogenous
Molecular Weight (kDa)	42
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	Protor-2 (D19A5) Rabbit mAb recognizes endogenous levels of total protor-2 protein.
Species Reactivity	Human, Monkey
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human protor-2 protein.
Background	Protein observed with rictor-1 (protor-1) and protor-2 both interact with rictor and were identified as components of mTORC2 (1). The absence of protor-1 or protor-2 does not affect the assembly of other mTORC2 components into an active complex (2). Protor-1 was shown to be essential for the activation of SGK1 mediated by mTORC2 (2). Protor-2 plays a role in tristetraprolin-mediated mRNA turnover (3).

Specifications