Cell Signaling Alpha-Tubulin (Dm1a) Mouse mAb (Hrp Conjugate)

Name: Cell Signaling Alpha-Tubulin (Dm1a) Mouse mAb (Hrp Conjugate)
SKU: CSIG-12351S
Price: 469.65 USD

List Price $469.65 Your Price $469.65

Cell Signaling Alpha-Tubulin (Dm1a) Mouse mAb (Hrp Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-12351S

MFG.PART: 12351S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H M R Mk
Sensitivity	Endogenous
Molecular Weight (kDa)	52
Source/Isotype	Mouse IgG1
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 136 mm NaCl, 2.6 mm KCI, 12 mm sodium phosphate (pH 7.4) dibasic, 2 mg/mL BSA, and 50% glycerol. Store at –20°C. Do not aliquot the antibodies.
Specificity/Sensitivity	α-Tubulin (DM1A) Mouse mAb (HRP Conjugate) recognizes endogenous levels of total α-tubulin protein.
Species Reactivity	Human, Mouse, Rat, Monkey
Source/Purification	Monoclonal antibody is produced by immunizing animals with full-length chicken α-tubulin purified from brain extracts, and recognizes residues surrounding Val440 of α-tubulin protein.
Background	The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. γ-tubulin is required to nucleate polymerization of tubulin subunits to form microtubule polymers. Many cell movements are mediated by microtubule action, including the beating of cilia and flagella, cytoplasmic transport of membrane vesicles, chromosome alignment during meiosis/mitosis, and nerve-cell axon migration. These movements result from competitive microtubule polymerization and depolymerization or through the actions of microtubule motor proteins (1).

Specifications