Cell Signaling Ppargamma (C26h12) Rabbit mAb

Name: Cell Signaling Ppargamma (C26h12) Rabbit mAb
SKU: CSIG-2435T
Price: 146.45 USD

List Price $146.45 Your Price $146.45

Cell Signaling Ppargamma (C26h12) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-2435T

MFG.PART: 2435T

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	20 µl
Reactivity	H M
Sensitivity	Endogenous
Molecular Weight (kDa)	53, 57
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunohistochemistry (Paraffin): 1:400 - 1:1600, Immunofluorescence (Immunocytochemistry): 1:50 - 1:200, Chromatin IP: 1:100, Chromatin IP-seq: 1:100}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.For a carrier free (BSA and azide free) version of this product see product #35264.
Specificity/Sensitivity	PPARγ (C26H12) Rabbit mAb detects endogenous levels of total PPARγ protein.
Species Reactivity	Human, Mouse
Source/Purification	PPARγ (C26H12) Rabbit mAb is produced by immunizing rabbits with a synthetic peptide corresponding to residues surrounding Asp69 of human PPARγ.
Background	Peroxisome proliferator-activated receptor γ (PPARγ) is a member of the ligand-activated nuclear receptor superfamily and functions as a transcriptional activator (1). PPARγ is preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage (2). Besides its role in mediating adipogenesis and lipid metabolism (2), PPARγ also modulates insulin sensitivity, cell proliferation and inflammation (3). PPARγ transcriptional activity is inhibited by MAP kinase phosphorylation of PPARγ at Ser84 (4,5).

Specifications