Cell Signaling Psd95 (7e3) Mouse mAb

Name: Cell Signaling Psd95 (7e3) Mouse mAb
SKU: CSIG-36233S
Price: 352.49 USD

List Price $352.49 Your Price $352.49

Cell Signaling Psd95 (7e3) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-36233S

MFG.PART: 36233S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	95
Source/Isotype	Mouse IgG1
Application/Dilution	{Western Blotting: 1:1000, Immunofluorescence (Frozen): 1:100, Immunofluorescence (Immunocytochemistry): 1:100}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. For a carrier-free (BSA and azide free) version of this product see product #37350.
Specificity/Sensitivity	PSD95 (7E3) Mouse mAb recognizes endogenous levels of total PSD95 protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the full length rat PSD95 protein.
Background	Postsynaptic Density protein 95 (PSD95) is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. These family members consist of an amino-terminal variable segment followed by three PDZ domains, an SH3 domain, and an inactive guanylate kinase (GK) domain. PSD95 is a scaffolding protein involved in the assembly and function of the postsynaptic density complex (1-2). PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs) (3). It is implicated in experience-dependent plasticity and plays an indispensable role in learning (4). Mutations in PSD95 are associated with autism (5).

Specifications