Cell Signaling Keratin 19 (Ba17) Mouse mAb

Name: Cell Signaling Keratin 19 (Ba17) Mouse mAb
SKU: CSIG-4558T
Price: 144.43 USD

List Price $144.43 Your Price $144.43

Cell Signaling Keratin 19 (Ba17) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-4558T

MFG.PART: 4558T

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	20 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	40
Source/Isotype	Mouse IgG1
Application/Dilution	{Western Blotting: 1:1000, Immunohistochemistry (Paraffin): 1:100 - 1:400}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	Keratin 19 (BA17) Mouse mAb detects endogenous levels of total keratin 19 protein. The antibody does not cross-react with other keratin proteins.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with detergent-insoluble extract of human mammary epithelial organoids.
Background	Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as research biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).

Specifications