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Cell Signaling Mers-Cov Membrane Protein (E2z4q) Rabbit mAb
List Price $354.51 Your Price $354.51
Cell Signaling Mers-Cov Membrane Protein (E2z4q) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
NETA PART: CSIG-56075S
MFG.PART: 56075S
UNSPSC: 12352203
Manufacturer: Cell Signaling
| Size | 100 µl |
| Reactivity | Vir |
| Sensitivity | Transfected Only |
| Molecular Weight (kDa) | 20-30 |
| Source/Isotype | Rabbit IgG |
| Application/Dilution | {Western Blotting: 1:1000} |
| Storage | Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. |
| Specificity/Sensitivity | MERS-CoV Membrane Protein (E2Z4Q) Rabbit mAb recognizes transfected levels of total MERS-CoV membrane protein. This antibody does not cross-react with membrane proteins from SARS coronaviruses (CoV-1, CoV-2). |
| Species Reactivity | Virus |
| Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln184 of MERS-CoV membrane protein. |
| Background | Middle East Respiratory Syndrome (MERS) is a contagious viral respiratory infection, whose causative agent was identified as the MERS-related coronavirus (MERS-CoV) (1,2). MERS-CoV is a single-stranded mRNA betacoronavirus; similar to other infectious coronaviruses (e.g., SARS-CoV-2), the MERS-CoV genome encodes four key structural proteins (spike, envelope, membrane, and nucleocapsid) that make up the virion particle, in addition to at least 10 smaller open reading frames (ORFs) that encode the non-structural (accessory) proteins required for viral replication (3). The MERS membrane protein, like that of other betacoronaviruses, is an integral membrane protein and the most abundant of the structural proteins in a virus particle. Numerous studies have shown that the membrane protein of betacoronaviruses is more than just a structural protein; it plays multiple functional roles in orchestrating viral replication following host infection (4-7). |
| SKU | CSIG-56075S |
|---|---|
| Supplier Part Number | 56075S |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | Cell Signaling |
| MSDS URL | Click here |
| Temperature | -20C |
| CountryOfOrigin | United States |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |