Cell Signaling Cd133 (A8n6n) Mouse mAb (Flow Specific)

Name: Cell Signaling Cd133 (A8n6n) Mouse mAb (Flow Specific)
SKU: CSIG-60577S
Price: 351.48 USD

List Price $351.48 Your Price $351.48

Cell Signaling Cd133 (A8n6n) Mouse mAb (Flow Specific) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-60577S

MFG.PART: 60577S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Source/Isotype	Mouse IgG3
Application/Dilution	{Flow Cytometry (Live): 1:50 - 1:200}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	CD133 (A8N6N) Mouse mAb recognizes endogenous levels of total CD133 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with cells overexpressing human CD133 protein.
Background	CD133, also known as Prominin, was first described as a cell surface marker recognized by monoclonal antibody AC133 on putative hematopoietic stem cells (1). Subsequent cDNA cloning indicated that CD133 is a five-transmembrane protein with a predicted molecular weight of 97 kDa. Due to heavy glycosylation, its apparent molecular weight is 130 kDa as determined by SDS-PAGE analysis (2). Besides blood stem cells, CD133 is expressed on and used to isolate other stem cells, including cancer stem cells (3-7). A deletion mutation in CD133 produces aberrant protein localization and may result in retinal degeneration in humans (8).

Specifications