Cell Signaling Fam96b (D4v9z) Rabbit mAb

Name: Cell Signaling Fam96b (D4v9z) Rabbit mAb
SKU: CSIG-86302S
Price: 342.39 USD

List Price $342.39 Your Price $342.39

Cell Signaling Fam96b (D4v9z) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-86302S

MFG.PART: 86302S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	18
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	FAM96B (D4V9Z) Rabbit mAb recognizes endogenous levels of total FAM96B protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln21 of human FAM96B protein.
Background	Iron-sulfur (Fe-S) clusters (ISC) are cofactors for many proteins that display a wide range of biological functions, such as DNA maintenance, transcription, translation, cellular metabolism, electron transport, and oxidative phosphorylation (1). While structurally simple, the synthesis and insertion of ISC into Fe-S proteins are complex processes that involve many different proteins (2). FAM96B, also known as MIP18 (MSS19-interacting protein of 18kDa), is a component of the cytosolic Fe-S protein assembly complex (3,4). FAM96B is in a complex with MMS19 that is responsible for assembly of multiple nuclear Fe-S proteins involved in DNA metabolism (5).

Specifications