Cell Signaling Ddx4 (D10c5) Rabbit mAb

Name: Cell Signaling Ddx4 (D10c5) Rabbit mAb
SKU: CSIG-8761S
Price: 357.54 USD

List Price $357.54 Your Price $357.54

Cell Signaling Ddx4 (D10c5) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-8761S

MFG.PART: 8761S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µl
Reactivity	H M
Sensitivity	Endogenous
Molecular Weight (kDa)	80
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:100, Immunofluorescence (Frozen): 1:200}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	DDX4 (D10C5) Rabbit mAb recognizes endogenous levels of total DDX4 protein.
Species Reactivity	Human, Mouse
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human DDX4 protein.
Background	DDX4 is an ATP-dependent DEAD-box RNA helicase found in the chromatoid body of the germ cells (1). This enzyme is specific to germ cells and is necessary for germ cell development (2). Mouse DDX4 was shown to interact with Dicer, suggesting a role in microRNA-mediated RNA silencing (1).