Cell Signaling Nanog (D2a3) Xp Rabbit mAb (Mouse Specific)

Name: Cell Signaling Nanog (D2a3) Xp Rabbit mAb (Mouse Specific)
SKU: CSIG-8822T
Price: 160.59 USD

List Price $160.59 Your Price $160.59

Cell Signaling Nanog (D2a3) Xp Rabbit mAb (Mouse Specific) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-8822T

MFG.PART: 8822T

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	20 µl
Reactivity	M
Sensitivity	Endogenous
Molecular Weight (kDa)	29-42
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:100, Immunofluorescence (Immunocytochemistry): 1:1000, Flow Cytometry (Fixed/Permeabilized): 1:200, Chromatin IP: 1:100, Chromatin IP-seq: 1:100, CUT&RUN: 1:100}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	Nanog (D2A3) XP® Rabbit mAb recognizes endogenous levels of total mouse nanog protein. This antibody is expected to recognize nanog 1a and 1b isoforms. This antibody does not cross-react with human nanog.
Species Reactivity	Mouse
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of mouse nanog protein.
Background	Nanog is a homeodomain-containing transcription factor that is essential for the maintenance of pluripotency and self renewal in embryonic stem cells (1). Nanog expression is controlled by a network of factors including Sox2 and the key pluripotency regulator Oct-4 (1). Recent advances in somatic cell reprogramming have utilized viral expression of combinations of transcription factors including nanog, Oct-4, Sox2, KLF4, c-Myc, and LIN28 (2,3).