Cell Signaling Epcam (E6v8y) Rabbit mAb (Mouse Preferred) (BSA And Azide Free)

Name: Cell Signaling Epcam (E6v8y) Rabbit mAb (Mouse Preferred) (BSA And Azide Free)
SKU: CSIG-88469SF
Price: 873.65 USD

List Price $873.65 Your Price $873.65

Cell Signaling Epcam (E6v8y) Rabbit mAb (Mouse Preferred) (BSA And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-88469SF

MFG.PART: 88469SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	35-45
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free. For standard formulation of this product see product #93790.
Specificity/Sensitivity	EpCAM (E6V8Y) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total EpCAM protein. This antibody is preferred for immunohistochemical analysis of mouse tissues.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg311 of mouse EpCAM protein.
Background	Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+-independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). Research studies identified EpCAM as one of the first tumor-associated antigens, and it has long been a marker of epithelial and tumor tissue. Investigators have shown that EpCAM is highly expressed in cancer cells (reviewed in 2,3).

Specifications