Cell Signaling Tslp (D7u1x) Rabbit mAb

Name: Cell Signaling Tslp (D7u1x) Rabbit mAb
SKU: CSIG-97630S
Price: 354.51 USD

List Price $354.51 Your Price $354.51

Cell Signaling Tslp (D7u1x) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-97630S

MFG.PART: 97630S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	19, 22
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	TSLP (D7U1X) Rabbit mAb recognizes endogenous levels of total TSLP protein. This antibody recognizes a 70 kDa protein of unknown identity.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant human TSLP protein.
Background	TSLP (thymic stromal lymphopoietin) is a cytokine produced by epithelial cells at barrier surfaces and granulocytes (1). TSLP acts on dendritic cells, lymphocytes, and granulocytes by binding to a heterodimer composed of TSLPR (TSLP receptor) and IL-7Rα (2-5). Constitutive expression of TSLP at barrier surfaces contributes to homeostasis by promoting generation of noninflammatory dendritic cells (6). TSLP promotes the differentiation of Th2 cells and type 2 immune responses both in response to helminth infection and in the context of atopic diseases including asthma and atopic dermatitis (1,7-12).

Specifications