Revvity Hemicholinium-3 Diacetate Salt, -, 250uCi (9.25MBq)

Revvity Hemicholinium-3 Is An Inhibitor That Blocks Reuptake Of Choline By The High-Affinity Choline Transporter. This Transporter Mediates Drug Delivery Across The Blood-Brain Barrier. We Offer Both Agonist And Antagonist Radioligands For Autoradiographic Visualization Or Performing Saturation And Competition Assays To Determine Receptor Expression Levels (Bmax), Dissociation Constants (Kd), Association And Dissociation Rates (Kon And Koff), And Inhibitor Constants (Ki) For A Variety Of Receptors. We Develop Our Radioligands To The Highest Specific Activity Possible And Provide High Purity Resulting In Low Non-Specific Binding Products. Each Of Our Ultra-Pure Radioligands Is Fully Characterized For Pharmacological Action And Validated In Receptor Binding Assays. Radiolabeled Ligands Remain The Most Sensitive Method For Probing Receptor Binding Biology; Yielding Unprecedented Sensitivity Gives Results That Technicians And Scientists Can Trust. For Over 50 Years, Perkin Elmer Has Been A Leading Supplier Of New England Nuclear (Nen) Radiochemicals, Liquid Scintillation Cocktails, Vials And Nuclear Counting Detection Instruments. References For Net884: Sekiguchi, K., Imamura, S., Yamaguchi, T., Tabuchi, M., Kanno, H., Terawaki, K., Kase, Y. And Ikarashi, Y. (2011), Effects Of Yokukansan And Donepezil On Learning Disturbance And Aggressiveness Induced By Intracerebroventricular Injection Of Amyloid ? Protein In Mice. Phytother. Res., 25: 501-507. Kri?Tofikov?, Z., Kopeck?, V., Hofbauerov?, K. Et Al. (2008) Complex Of Amyloid ? Peptides With 24-Hydroxycholesterol And Its Effect On Hemicholinium-3 Sensitive Carriers. Neurochem Res., 33: 412.S - PEGSK (Additional S&H Or Hazmat Fees May Apply)