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Beckman Ige (Dε2)-Unlb, E124.2.8, 0.2 Mg, ASR
List Price $517.25 Your Price $517.25
Beckman Anti-Human Ige (D 2), 0.2 Mg Asr - BCKM (Additional S&H or Hazmat Fees May Apply)
NETA PART: BCKM-A40174
MFG.PART: A40174
UNSPSC: 41116001
Manufacturer: Beckman Coulter


The anti-IgE mAb binds to circulating IgE as well as to IgE antibodies bound to the low affinity receptor FcεRII (expressed mainly on eosinophils, B lymphocytes), or to the high affinity receptor FcεRI (expressed on mast cells, basophils, monocytes and monocytes-derived cells). The anti-IgE antibody induces the histamine release from basophils. However, it is known in the literature information that basophils from 10% to 20% of donors completely fail to release histamine in response to anti-IgE, designated anti-IgE "non releasers".
Product Specifications
| Target Species | Human |
| Specificity | IgE (Dε2) |
| Fluorochrome | UNLB |
| Regulatory Status | ASR |
| Size | 0.2 mg |
| Format | Freeze-dried |
| Clone | E124.2.8 |
| Isotype | IgG1 Mouse |
| Clone Description | The E124.2.8 monoclonal antibody binds specifically to the Dε2 constant domain of human Immunoglobulin E (IgE) (Dε2 is the heat labile region of IgE). |
| SKU | BCKM-A40174 |
|---|---|
| Supplier Part Number | A40174 |
| UM | EA |
| UNSPSC | 41116001 |
| Manufacturer | Beckman Coulter |
| ProductLine | BCKM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 21 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |

